JBEI researchers in the Technology Division investigate new technologies to advance the research and development of biofuels and bioproducts. Technologies being used to help JBEI reach its scientific goals include techniques for the characterization of genes and proteins in both natural and engineered plants and microorganisms, synthetic biology techniques for engineering new plants and fuel-generating organisms, and high resolution structural analysis of the enzymes involved in plant cell wall synthesis, biomass degradation, and the microbial synthesis of biofuels and bioproducts.

High-throughput methods, using microfluidics and array technologies, have been developed to enable rapid screening of lignocellulose breakdown, enzyme activities, and fuel production. In addition, JBEI Technology Division researchers provide resources for data management, analysis and visualization through a combination of commercial, open-source and custom software products. The goal is to understand plant and microbial systems, and proteins at a level whereby enzymes and strains can be engineered to promote the deconstruction of cellulosic biomass and subsequent synthesis of biofuels and bioproducts.

visit page Microfluidics


High-throughput and high-content assay technologies are being developed for characterizing enzymes.

visit page Functional Genomics

Functional Genomics

State-of-the-art mass spectrometry methods to provide metabolite and protein characterization for JBEI research.

visit page High Throughput Biochemistry

High Throughput Biochemistry

Integrating nano-fabrication with bioconjugate chemistries to develop and deploy high sensitivity, specificity, and throughput mass spectrometry assays that support enzyme discovery and synthetic biology.

visit page Synthetic Biology Informatics

Synthetic Biology Informatics

Continuous development and maintenance of SynBio software infrastructure and operation of DIVA DNA construction and sequence validation services.

visit page Structural Biology

Structural Biology

Structural biology methods are used to understand and engineer biofuel and bioproduct enzymes.