Dominique Loque

Former: Feedstocks
Current: Bayer Crop Science

Curriculum vitae

Research Interests

Synthetic biology, Molecular biology, Metabolic engineering,
Plants, Cell wall, Lignin, Plant Physiology, Nutrient transport, Plant nutrition, Nitrogen acquisition, Plant-microbe interactions,
Yeast, Phenylpropanoid pathway, Aromatic amino acid biosynthesis

Main Projects

JBEI:

Developing novel and dominant approaches to reduce lignin content and/or modify its composition to valorize its downstream utilization
Developing synthetic biology tools to support metabolic engineering in plants and biomass optimization
Stacking bioenergy traits to developed optimized bioenergy crops

Non-JBEI:

Developing promoter libraries to facilitate plant root engineering
Engineering metabolic pathway in plant roots to improve plant-microbe interactions and nutrient acquisition

Featured Media

JBEI Expert Dominique Loqué discusses the study of plant cell walls

2014 R&D 100 Winner – Lawrence Berkeley National Laboratory’s Tissue-Specific Cell-Wall Engineering

Director’s 2014 Lifetime and Exceptional Achievement Award

2014 Robert Rabson Award – Dominique Loqué

Five Berkeley Lab Researchers Receive DOE Early Career Awards

Swords to Plowshares: Engineering Plants for More Biofuel sugars

Making Do with More: Joint BioEnergy Institute Researchers Engineer Plant Cell Walls to Boost Sugar Yields for Biofuels

Featured Publications

“Exploiting the substrate promiscuity of hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl transferase to reduce lignin”, Plant Cell Physiology (2016)
“Expression of S-adenosylmethionine Hydrolase in Tissues Synthesizing Secondary Cell Walls Alters Specific Methylated Cell Wall Fractions and Improves Biomass Digestibility”, Front. Bioeng. Biotechnol (2016)
“Biotechnology and synthetic biology approaches for metabolic engineering of bioenergy crops”, Plant Journal (2016)
“Precursor-directed combinatorial biosynthesis of cinnamoyl, dihydrocinnamoyl, and benzoyl anthranilates in Saccharomyces cerevisiae”, PLoS one (2015)
“Standards for Plant Synthetic Biology: A Common Syntax for Exchange of DNA Parts”, New Phytologist (2015)
“Engineering of plant cell walls for enhanced biofuel production”, Curr Opinion Plant Biol. (2015)
“Expression of a bacterial 3-dehydroshikimate dehydratase reduces lignin content and improves biomass saccharification efficiency”, Plant Biotechnology Journal (2015)
“Engineering temporal accumulation of a low recalcitrance polysaccharide leads to increased C6 sugar content in plant cell walls”, Plant Biotechnology Journal (2015)
“A gene stacking approach leads to engineered plants with highly increased galactan levels in Arabidopsis”, BMC Plant Biology (2014)
“Lignin bioengineering”, Current Opinion in Biotechnology (2014)
“Visualization of Plant Cell Wall Lignification Using Fluorescence-tagged Monolignols”, Plant Journal (2013)
“Production of hydroxycinnamoyl anthranilates from glucose in Escherichia coli” Microbial Cell Factories (2013)
“Engineering of plants with improved properties as biofuels feedstocks by vessel-specific complementation of xylan biosynthesis mutants” Biotechnoly for Biofuels (2013)
“Engineering secondary cell wall deposition in plants” Plant Biotechnology Journal (2013)
“Biosynthesis and incorporation of side-chain-truncated lignin monomers to reduce lignin polymerization and enhance saccharification” Plant Biotechnology Journal (2012)

Featured Intellectual Property