Bernhard Palsson

Scientific Lead, Host Engineering

Bernhard Ø. Palsson is the Galletti Professor of Bioengineering, Professor of Pediatrics, and the Principal Investigator of the Systems Biology Research Group in the Department of Bioengineering at the University of California, San Diego. He previously held a faculty position at the University of Michigan for 11 years and was named the G.G. Brown Associate Professor at Michigan in 1989.

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Research Focus

His research includes the development of methods to analyze metabolic dynamics (flux-balance analysis, and modal analysis), and the formulation of complete models of selected cells (the red blood cell, E. coli, CHO cells, and several human pathogens). He sits on the editorial board of several leading peer-reviewed microbiology, bioengineering, and biotechnology journals.

He is inventor on over 40 U.S. patents, the co-founder of several biotechnology companies, and holds several major biotechnology awards. He received his PhD in Chemical Engineering from the University of Wisconsin, Madison in 1984. Dr. Palsson is a member of the National Academy of Engineering and is a Fellow of both the AAAS and the AAM.


  • Development of a retrobiosynthesis platform
  • Software tool integration
  • Formulation of strain-specific models
  • Assessment of host factors for optimal pathway function

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