Bernhard Ø. Palsson is the Galletti Professor of Bioengineering, Professor of Pediatrics, and the Principal Investigator of the Systems Biology Research Group in the Department of Bioengineering at the University of California, San Diego. He previously held a faculty position at the University of Michigan for 11 years and was named the G.G. Brown Associate Professor at Michigan in 1989.
Personal Website: http://systemsbiology.ucsd.edu/Researchers/Palsson/
Group Website: http://systemsbiology.ucsd.edu/
Research Focus
His research includes the development of methods to analyze metabolic dynamics (flux-balance analysis, and modal analysis), and the formulation of complete models of selected cells (the red blood cell, E. coli, CHO cells, and several human pathogens). He sits on the editorial board of several leading peer-reviewed microbiology, bioengineering, and biotechnology journals.
He is inventor on over 40 U.S. patents, the co-founder of several biotechnology companies, and holds several major biotechnology awards. He received his PhD in Chemical Engineering from the University of Wisconsin, Madison in 1984. Dr. Palsson is a member of the National Academy of Engineering and is a Fellow of both the AAAS and the AAM.
Projects
- Development of a retrobiosynthesis platform
- Software tool integration
- Formulation of strain-specific models
- Assessment of host factors for optimal pathway function
Featured Publications
Complete list of publications from: http://systemsbiology.ucsd.edu/Publications
- “What is flux balance analysis?.”, Nature biotechnology (2010)
- “A genome‐scale metabolic reconstruction for Escherichia coli K‐12 MG1655 that accounts for 1260 ORFs and thermodynamic information.”, Molecular systems biology (2007)
- “Global reconstruction of the human metabolic network based on genomic and bibliomic data.”, Proceedings of the National Academy of Sciences (2007)
- “Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network”,Genome research (2003)
- “In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data.”, Nature biotechnology (2001)
- “An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR).”, Genome biology (2003)
Featured Intellectual Property
Complete list of patents from: http://systemsbiology.ucsd.edu/Researchers/Palsson/patents