Anup Singh

Director of Microfluidics

Research Focus

Anup Singh is the Principal Associate Director for Engineering at at Lawrence Livermore National Laboratory, Livermore, CA. . In this role, he leads an organization of approximately 2,700 engineering professionals with responsibility for the full breadth of the Laboratory’s engineering needs to support  Laboratory’s missions in Nuclear Deterrence, Countering WMD Threats, and Climate and Energy Security. 

He is internationally recognized for his scientific leadership in microfluidics and has published more than 100 peer-reviewed publications, delivered more than 150 presentations at national and international conferences, and his inventions have led to more than 40 patents and patent applications. Many of his inventions have been licensed to companies engaged in medical diagnostics and sensor technology development.

His group’s aim is to create specialized technologies to support the scientific research in feedstock development, biomass degradation, and fuel conversion for efficient conversion of biomass to biofuels. These technologies include an integrated microfluidic platform for metabolic engineering of organisms that integrate DNA assembly, transformation, and cell culture. His group is collaborating with Hector Garcia-Martin’s group to integrate these high-throughput experimental platforms with AI/ML towards developing self-driving laboratories for enabling predictive metabolic engineering. 


Microfluidic and Array-based assays

  • Adapt electrophoretic glycan analysis to a commercial microfluidic instrument and demonstrate screening of GT and GH enzymes in 96-well format.
  • Develop a droplet microfluidic system for highly-parallel analysis. Demonstrate in this platform a) screening of multiple cellulose cocktails using insoluble biomass with Deconstruction and b) assembly of genes using multiple cloning methods with Fuels Synthesis.


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