Issued Patents

JBEI has an expanding patent portfolio of US and global patent applications, leading to an increasing number of issued patents. To date, the following patents have been issued:

IP NumberCountryIP TitleInventorsLBNL Ref.
17985567USHost Cells and Methods for Producing 3-Methyl-2-buten-1-ol, 3-Methyl-3-buten-1-ol, and 3-Methyl-butan-1-olHoward H. Chou and Jay Keasling2392-01
28420833USProducing Biofuels Using Polyketide SynthasesJeffrey L. Fortman, Leonard Katz and Jay Keasling2540-01
38569023USProducing Dicarboxylic Acids Using Polyketide SynthasesJeffrey L. Fortman, Leonard Katz and Jay Keasling 2541-01
48552169USTranscription factor-based biosensor Jeffrey Dietrich and Jay Keasling2710-01
58790542USNovel compositions and methods useful for ionic liquid treatment of biomass, InvDean C. Dibble, Aurelia A.Cheng and Anthe George2729-01
68652804USTranscription factor-based biosensors for detecting dicarboxylic acids Jeffrey Dietrich and Jay Keasling2982-01
79040282USProducing Dicarboxylic Acids Using Polyketide Synthases,Jeffrey L. Fortman, Leonard Katz and Jay Keasling 2541-08
88852902USProducing a Trimethylpentanoic Acid Using Hybrid Polyketide SynthasesJeffrey L. Fortman, Leonard Katz and Jay Keasling2825-01
99109175USIsoprenoid Based Alternative Diesel FuelJay Keasling, Taek Soon Lee and Pamela Patricia Peralta-Yahya 2837-01
109157130USRecovery of Sugars from Ionic Liquid Biomass Liquor by Solvent ExtractionHarvey W. Blanch, Bradley Holmes, Timothy Brennan and Blake A. Simmons2750-01
119200298USHost Cells and Methods for Producing Isoprenyl AlkanoatesTaek Soon Lee, Jeffrey L. Fortman and Jay Keasling2391-01
129290768USEngineered Microorganisms Having Resistance to Ionic LiquidsMichael Thelen and Thomas L. Ruegg3127-02
139322042USThermophilic Cellulases Compatible with Ionic Liquid Pretreatment for Simultaneous Pretreatment and Saccharification of Cellulosic BiomassHarvey W. Blanch, Rajat Sapra, Bradley Holmes, Zhiwei Chen, Supratim Datta and Blake A. Simmons2666-01
149334514USHybrid Polyketide SynthasesJeffrey Fortman, Leonard Katz, Jay Keasling, Sean Poust, Jingwei Zhang and Sergey Zotchev2820-01
159376691USFusion Proteins Useful for Producing PinenePamela Patricia Peralta-Yahya and Jay Keasling 2895-03
169361427USScar-Less Multi-Part DNA Assembly Design AutomationNathan J. Hillson 2928-01
179376728US Useful halophilic, thermostable and ionic liquids tolerant cellulasesTao Zhang, Supratim Datta, Edward M. Rubin and Blake A. Simmons3028-02
189382553USHost Cells and Methods for Producing 1-Deoxyxylulose 5-phosphate (DXP) and/or a DXP Derived CompoundJames Kirby, Jeffrey L Fortman, Minobu Nishimoto and Jay Keasling 3006-01
199403915USCompositions and methods useful for ionic liquid treatment of biomassDean C. Dibble, Aurelia Cheng and Anthe George2729-03
209428726USModified Host Cells with Efflux PumpsJay Keasling, Aindrila Mukhopadhyay and Mary J Dunlop2845-01
219556458USBacterial Production of Methyl KetonesHarry R Beller and Ee-Been Goh3063-03
229624482USNovel thermophilic cellobiohydrolaseRajat Sapra, Joshua Park, Supratim Datta and Blake A. Simmons2745-01
239631210US
Methods For Increasing Production Of 3-Methyl-2-Butenol Using Fusion ProteinsHoward H Chou and Jay Keasling3112-03
249637766USHost Cells and Methods for Producing 1-Deoxyxylulose 5-phosphate (DXP) and/or a DXP Derived Compound (Divisional)James Kirby, Jeffrey L Fortman, Minobu Nishimoto and Jay Keasling3006-03
259708624USModulation of Expression of Acyl Transferases to Modify Hydroxycinnamic Acid ContentLaura E Bartley, Pamela C Ronald and Henrik Vibe Scheller2915-03
269725749USGlycoside Hydrolases Having Multiple Hydrolase ActivitiesSwapnil R Chhabra, Dylan C Chivian, Zhiwei Chen, Gregory Friedland and Blake A. Simmons3057-03
279745587USNovel Nucleic Acid Constructs Containing Orthogonal Site Selective Recombinases (OSSRs)Joshua M Gilmore, John E Dueber and J. Christopher Anderson2593-01
289738901USRegulation of Galactan Synthase Expression to Modify Galactan Content in PlantsHenrik Vibe Scheller and Joshua L Heazlewood3144-03
299765044USSynthesis of Novel Ionic Liquids from Lignin-Derived Compounds Blake A. Simmons, Seema Singh, Aaron M. Socha and Maxime Bergeron2013-042-04
30
9803182US
Ionic Liquid-Tolerant Cellullase Enzymes Blake A. Simmons, Joshua Park, Kenneth L. Sale, Steven W Singer and John M Gladden3264-02
31103403016ChinaSpatially Modified Gene Expression in PlantsDominique Loque and Henrik Vibe Scheller2930-06
329816101US
Improving Drought and Submergence Tolerance in PlantsPamela C Ronald, Hewei Du, Yufan Zhou and Nir Oksenberg2014-108-03
3312842733.3FranceBacterial Production of Methyl Bacterial Production of Methyl KetonesHarry R Beller and Ee-Been Goh3063-05
34 602012040706.9 GermanyBacterial Production of Methyl KetonesHarry R Beller and Ee-Been Goh3063-06
3512842733.3UKBacterial Production of Methyl KetonesHarry R Beller and Ee-Been Goh3063-07
369856461US
Producing alpha-olefins using polyketide synthasesJeffrey L Fortman, Leonard Katz, Eric J Steen and Jay Keasling2809-17
379862982USUseful halophilic, thermostable and ionic liquids tolerant cellulasesTao Zhang, Supratim Datta, Edward M. Rubin;Blake A. Simmons *3028-03
389902964
USGrowth Arrested Cells Useful for Producing CompoundsJay Keasling and Gregory Bokinsky
2014-061-02
399932601
USInhibition of Snl6 Expression for Biofuel ProductionBecky Bart, Mawsheng Chern, Pamela C Ronald and Miguel Vega-Sanchez
2763-03
409951345
USHost Cells and Methods for Producing Diacid CompoundsJay Keasling, Eric J Steen, Jeffrey L Fortman and Jeffrey Dietrich
2878-01
412771381EPOBacterial Production of Methyl KetonesHarry R Beller and Ee-Been Goh3063-04
4210112916USHMF Production from Fructose in Ionic Liquid MediaBlake A. Simmons, Anthe George, Seema Singh, Noppadon Sathitsuksanoh, Robert Jansen and Philip Travisano2014-136-02
4310131903USMicrofluidic Platform for Synthetic Biology ApplicationsNathan J Hillson, Anup K Singh, Rajiv Bharadwaj, Aarthi Chandrasekaran and Chieh Chang2934-01
4410155735USSynthesis of Novel Ionic Liquids from Lignin-Derived CompoundsBlake A. Simmons, Seema Singh, Aaron M. Socha and Maxime Bergeron2013-042-07
4510167488USHeterologous Pathway to Produce TerpenesJay Keasling and Christopher Eiben2014-119-02
4610227573USDominant negative mutations of Arabidopsis RWAHenrik Scheller, Dominique Loque and Soe Htwe2013-051-02
4710208076USRenewable Aromatics From Lignocellulosic LigninBlake A. Simmons, Seema Singh and Patanjali Varanasi2013-105-02
4810233431USProducing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide SynthasesJay D. Keasling, Leonard Katz and Satoshi Yuzawa2014-007-02
4910167488USHeterologous Pathway to Produce TerpenesJay D. Keasling and Christopher Eiben 2014-119-02
5010273506USNovel Host Cells and Methods for Producing Isopentenol from MevalonateTaek Soon Lee and Aram Kang2014-135-03
5110280441USHost Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs ThereofDominique Loque and Aymerick Eudes2923-01
5210240180USMultiplexed Screening of Enzyme Activities Using Nanostructure-Initiator Mass SpectrometryTrent R Northen, Seema Singh, Anup K Singh, Wolfgang E Reindl, Kai Deng and Xiaoliang Cheng2926-01
5310233457USInhibition of a Xylosyltransferase to Improve Sacharification EfficiencyHenrik Scheller, Dawn M. Chiniquy and Pamela C Ronald3136-02
5410233292USRenewable Aromatics from Lignocellulosic LigninBlake A. Simmons, Seema Singh and Patanjali Varanasi3265-03
5510227622USA Host Cell Modified to Produce 2-PyrrolidoneJay D. Keasling and Jingwei Zhang3307-02
5657.232ChileSpatially Modified Gene Expression in PlantsDominique Loque and Henrik Scheller2930-05
5710316068USSynthetic Polypeptide Having A Xylose Import ActivityAindrila Mukhopadhyay, Amanda Reider Apel, Mario Ouellet and Jay D. Keasling2014-020-02
5810351881USHost Cells and Methods for Producing Diacid
Compounds
Jay D. Keasling and
Robert Haushalter
2014-158-02
5910358685USSugar Extraction and Ionic Liquid Recycling Using Alkaline SolutionsBradley Holmes, Anthe George, Ning Sun, Kim Tran, and Blake Simmons3117-03
6010358651USModified Plants and Methods for Producing Modified Lignin by Modulating Expression of AcyltransferasesDominique Loque Aymerick Eudes2013-139-02
6110370686USA Yeast Cell Modified to Overproduce Fatty Acid and Fatty Acid-Derived CompoundsJay Keasling Weerawat Runguphan2013-113-03
6210370418USEngineered Microorganisms Having Resistance to Ionic LiquidsThomas Ruegg Michael Thelen Douglas Higgins2013-120-02
6310373703USScar-Less Multi-Part DNA Assembly Design AutomationNathan Hillson2928-03
6410378000USIonic Liquid-Tolerant Cellulase EnzymesBlake Simmons Joshua Park Kenneth Sale Steven Singer John Gladden3264-03
6510407691USEngineering Pathogen Resistance in PlantsPamela Ronald Benjamin Schwessinger Rory Pruitt Anna Joe Weiguo Zhang2016-030-03
6610415052USTissue specific reduction of ligninDominique Loque Aymerick Eudes3266-03
6710450578USModulation of Expression of Acyltransferases to Modify Hydroxycinnamic Acid ContentLaura Bartley Pamela Ronald Henrik Scheller2915-04
6810494625USHybrid Polyketide SynthasesJeffrey Fortman Jay Keasling Andrew Hagen Sean Poust Jingwei Zhang SergeyZotchev Leonard Katz2820-04
6910513713USModified Host Cells having Tolerance to Alpha-OlefinsFlorence Mingardon Angelique Chanal Aindrila Mukhopadhyay2013-181-03
7010557152USYeast Host Cells and Methods for Producing Fatty AlcoholsJay Keasling Leopold D'Espaux2017-097-02
7110597669USMethod of Reducing Acetylation in Plants to Improve Biofuel ProductionHenrik Scheller2658-04
7210597685USHost Cells and Methods for Oxidizing Aromatic Amino AcidsJay Keasling Yasuharu Satoh Taek Soon Lee2939-01
7310640537USHost Cells and Methods Using a Repressor Polypeptide and an Inducible Promoter for Gene ExpressionThomas Ruegg2015-007-02
7410672601USDetecting Compounds in Microfluidic Droplets Using Mass SpectrometryTrent Northen Joshua Heinemann2016-049-03
7510696954USA Plant-Fungal Hybrid Peroxidase Engineered for Enhanced Activity and StabilityBlake Simmons Kenneth Sale Amanda Kohler2016-070-02
7610703770USNovel Compositions and Methods for the Dissolution and Depolymerization of LigninBlake Simmons Seema Singh Jian Sun Tanmoy Dutta Parthasarathi Ramakrishnan2015-080-02
7710767027USMagnetically-Recoverable Catalysts for DepolymerizationBlake Simmons Seema Singh Jian Sun2018-055-02
7810774338USGeneration of Heritable Chimeric Plant TraitsDominique Loque Yan Liang2013-171-02
7910814724USNovel Host Cells and Methods for Producing Isopentenol from MevalonateTaek Soon Lee Aram Kang2014-135-04
8010822634USDetermination of Ligninase Activities by Nano-structure Initiator Mass SpectrometryTrent Northen Kai Deng2016-109-03
8110837038USAdjusting the pH of a Pretreatment Solution Using Carbon Dioxide Useful for Integrating Saccharification and FermentationBlake Simmons Seema Singh Jian Shi Jian Sun2014-139-03
823475450USNucleic Acid Synthesis and Sequencing Using Tethered Nucleoside TriphosphatesDaniel Arlow Sebastian Palluk2018-103-07
8310876139USHost cells and Methods for Producing Diacid CompoundsJay Keasling Robert Haushalter2014-158-03
8410900049USTissue Specific Reduction of LigninDominique Loque Aymerick Eudes3266-06
8510907184USAmmonium Based Ionic Liquids Useful for Lignocellulosic ProcessingBlake Simmons Seema Singh Parthasarathi Ramakrishnan Tanmoy Dutta2014-167-03
8610913935USA Modified Bacteria Useful for Producing an Organic MoleculeHarry Beller3228-02
8710920231USSystems and Methods for Enhancing Gene ExpressionDominique Loque3293-03
8810934321USRenewable Aromatics from Lignocellulosic l-LigninBlake Simmons Seema Singh Noppadon Sathitsuksanoh Jian Shi Ning Sun Anthe George Manali Sawant2013-105-03
8910934568USConversion of Sugars to Ionic LiquidsBlake Simmons Seema Singh John Gladden Jian Sun Tanmoy Dutta2015-059-03
9010934551USGene Targets for Improved Enzyme Production in FungiJohn Gladden Scott Baker Jon Magnuson Jed Lynn Morgann Reilly Joonhoon Kim2015-059-03
9110941388USA Novel Cellulase Complex and Glycosidase Hydrolases Thereof, and Methods of Using ThereofSteven Singer John Gladden Jennifer Hiras Evelyn Denzel Sebastian Kolinko2015-010-03
9211001838USNovel Platform for Screening Phosphomevalonate DecarboxylaseTaek Soon Lee Aram Kang2016-110-02
9311014951USNovel Compositions and Methods for Depolymerizing Lignin Using a Chelator-Mediated Fenton ReactionMichael Kent2015-029-02
9411021525USA Synthetic Transcription Factor and Uses ThereofHoward Chou Jay Keasling Sergey Zotchev3211-03
9511028249USMethods of Synthesizing Ionic Liquids from Primary Alcohol-Containing Lignin CompoundsBlake Simmons Seema Singh Tanmoy Dutta2014-166-02
9611046981USA Host Cell Modified to Produce LactamsJay Keasling Jingwei Zhang2016-119-03
9711078499USHost Cells and Methods for Producing Toluene BiochemicallyHarry Beller Kamrun Zargar Andria Rodrigues2017-126-02
9811085048USLignification Reduction in PlantsDominique Loque Aymerick Eudes2929-09
9911118204USSwitchable Ionic Liquids for Biomass Pretreatment and Enzymatic HydrolysisBlake Simmons Kenneth Sale Michael Liszka2014-064-03
10011118197USHigh Gravity, Fed-Batch Ionic Liquid Based Process for Deconstructing BiomassBlake Simmons Seema Singh Feng Xu2015-143-03
10111160277USUse of Cholinium Lysinate as an HerbicideAindrilla Mukhopadhyay Robin Herbert Jennifer Mortimer Thomas Eng2018-118-02
10211185862USDigital Microfluidic Systems with Electrode Bus and Methods for Droplet ManipulationAnup Singh Philip Gach2017-053-02
10311193133USModulation of Expression of Acyl Transferases to Modify Hydroxycinnamic Acid ContentLaura Bartley Pamela Ronald Henrik Scheller2915-05
10411208666USMutant Xylan Biosynthetic Enzymes Capable of Dominant Suppression of Xylan BiosynthesisHenrik Scheller Dominique Loque Andrew Brandon2017-008-02
10511254637USConversions of Lignin to Ionic LiquidsBlake Simmons Seema Singh Jian Sun Tanmoy Dutta2015-055-03
10611254961USNucleic Acid Synthesis and Sequencing Using Tethered Nucleoside TriphosphatesDaniel Arlow Sebastian Palluk2018-103-03
10711299519USHost Cells and Methods Using a Repressor Polypeptide and an Inducible Promoter for Gene ExpressionThomas Ruegg2015-007-03
10810934551US Host cells and methods for producing isopentenol from mevalonate John Gladden, Scott Baker, Jon Magnuson, Jed Lynn, Morgann Reilly, Joonhoon Kim2017-118-02
1092940516CASynthesis of novel ionic liquids from lignin-derived compoundsBlake Simmons, Seema Singh, Aaron Socha, Maxime Bergeron2013-042-06
11011085048USLignification reduction in plantsDominique Loque, Aymerick Eudes2920-09
11111384367USSynthesis of bioproducts from lignin-derived aromatics by genetically modified microorganisms"Jay Keasling, John M Gladden, Jeffrey Skerker, James Kirby, Junko Yaegashi2015-057-03
11211369962USMethod and device for tracking and manipulation of dropletsAnup Singh, Jess Sustarich, Chao Chung Shih, Philip Gach2013-128-03
11311365431USYeast cells and methods for producing fatty alcoholsJay Keasling, Leopold D’Espaux2017-097-03
11411414653USPromoter useful for high expression of a heterologous gene of interest in Aspergillus nigerBlake Simmons, John Gladden, Jinxiang Zhang, Saori Campen, Jon Magnuson, Scott Baker2016-092-02
1153029320CANucleic acid synthesis and sequencing using tethered nucleoside triphosphatesDaniel Arlow, Sebastien Palluk2018-103-05
11611495328USArrowland: an online multiscale interactive tool for -omics data visualizationHector Garcia Martin, Garrett Birkel, William Morrell, Ling Liang, Mark Forrer2016-102-03
11711505810USHost cells and methods for producing alkyl lactone by cyclization of hydroxyl fatty acidJay Keasling, Robert Haushalter2016-054-03
11811505791USHybrid polyketide synthasesClem Fortman, Jay Keasling, Andrew Hagan, Sean Poust, Jingwei Zhang, Sergey, Zotchev, Leonard Katz2820-05
11911636917USSimulating the metabolic pathway dynamics of an organismHector Garcia Martin, Zachary Costello2017-049-02
12011624079USNucleic acid synthesis and sequencing using tethered nucleoside triphosphatesDan Arlow, Sebastian Palluk2018-103-12
12111660961USHost cells and methods for producing isopentenol from mevalonateTaek Soon Lee, Aram Kang2014-135-05
122EP3825412EPNucleic acid synthesis and sequencing using tethered nucleoside triphosphatesDaniel Arlow, Sebastian Palluk2018-103-10
12311732283USNucleic acid synthesis and sequencing using tethered nucleoside triphosphatesDaniel Arlow, Sebastian Palluk2018-103-11
12411718854USGene targets for improved enzyme production in fungJohn Gladden, Scott Baker, Jon Magnuson, Jed Lyn, Morgann Reilly, Joonhoon Kim2017-118-03
12511738321USGene targets for improved enzyme production in fungiTrent Northen, Anup Singh, Kai Deng, Todd Duncombe2016-121-03
12611739339USTranslation control tool for plantsDominique Loque, Yan Liang2013-166-02
12711746336USProducing 3-hydroxycarboxylic acid and ketone using polyketide synthasesJay Keasling, Leonard Katz, Satoshi Yuzawa2014-007-03
12811749379USScar-less multi-part DNA assembly design automationNathan Hillson2014-007-03
12911767521USGenetically modified bacterial cells and methods useful for producing indigoidineAindrila Mukhopadhyay, Thomas Eng, Deepanwita Banerjee2019-145
1302017280335AUNucleic acid synthesis and sequencing using tethered nucleoside triphosphatesDaniel Arlow, Sebastian Palluk2018-103-04
13111845940USGenetically modified fungal cells and methods useful for producing prespataneBlake Simmons, Taek Soon Lee, James Kirby, John Gladden, Gina Geiselman2019-014-02
13211884620USUse of polyamines in the pretreatment of biomassBlake Simmons, John Gladden, Venkataramana Pidatala, Lalitendu Das, Harsha Magurudeniya, Kaixuan Huang, Ezinne Achinivu, Mood Mohan, Hemant Choudhary2020-034-02
13311873498USTissue specific reduction of ligninDominique Loque, Aymerick Eudes3266-07
13411932896USHost cells and methods for producing hydroxytyrosolTaek Soon Lee, Erika Yoshita2016-118-03
13511939618USFusion proteins useful for modifying terpenesTaek Soon Lee, Xi Wang2019-109-02
13611976311USMethod of adjusting the pH of a pretreatment solution using carbon dioxide useful for integrating saccharification and fermentation of a biomassBlake Simmons, Seema Singh, Ning Sun, Jian Shi, Jian Sun2014-139-04
13712012429USRenewable aromatics from lignocellulosic ligninBlake Simmons, Anthe George, Seema Singh, Ning Sun, Jian Shi, Manali Sawant, Noppadon Sathitsuksanoh2013-105-04
138112015022211BRMethods of engineering a plant having reduced lignin content and obtaining an increased amount of soluble sugars from a plant in a saccharifying reactionDominique Loque, Aymerick Eudes3266-04
1392940141CATissue specific reduction of ligninDominique Loque, Aymerick Eudes3266-05
1407058228JPNucleic acid synthesis and sequencing using tethered nucleoside triphosphatesDaniel Arlow, Sebastien Palluk2018-103-09
141109642255CNNucleic acid synthesis and sequencing using tethered nucleoside triphosphates Daniel Arlow, Sebastien Palluk2018-103-06
142201817048968INNucleic acid synthesis and sequencing using tethered nucleoside triphosphatesDaniel Arlow, Sebastien Palluk2018-103-08
1433825412DENucleic acid synthesis and sequencing using tethered nucleoside triphosphatesDaniel Arlow, Sebastien Palluk2018-103-20