Paul Adams

Vice President for Technology and Director of Structural Biology

Research Focus

The development of new technologies to facilitate and accelerate the conversion of biomass to biofuels, including high throughput laboratory technologies and computational and information systems. The primary goals of the Technology Division are to provide a suite of technologies to support scientific discovery in all of the JBEI Divisions.

Technology Division Projects

  • Automating, parallelizing and miniaturizing procedures that are currently throughput-limiting in biofuels research
  • Developing new microfluidic, array and proteomics technologies for enzyme and protein characterization for biofuels research
  • High resolution imaging of plant cell walls using electron microscopy, and structural characterization of biofuels and bioproducts enzymes using X-ray crystallography and cryo-electron microscopy
  • Developing informatics systems to support large scale research

 

Featured Media

Crystallization Screen Created by JBEI Scientists Reaches the Market

Finding Diamonds in the Rough

Microfluidic Device Mixes And Matches DNA For Synthetic Biology

Cold Spring Harbor Laboratory Seminar: Synthetic Biology Scalability and Responsible Innovation

Clearing a Potential Road Block to Bisabolane

JBEI researchers determined the structure of the AgBIS enzyme and found it to consist of three helical domains, the first three-domain structure ever found in a synthase of sesquiterpenes. This discovery holds importance for advanced biofuels and other applications.

Starting a New Metabolic Path: JBEI and Berkeley Lab Researchers Develop Technique to Help Metabolic Engineering

Schematic of targeted proteomics technique in which a peptide mass and a specific fragment mass are selected for SRM mass spectrometry analysis to identify and quantify a target protein. (Image from Christopher Petzold)

JBEI’s Director of Array-Based Assays, Trent Northen, Wins R&D 100 Award

High-Throughput Nanostructure-Initiator Mass Spectrometry (HT-NIMS) is a high-speed chemical screening system that can precisely determine the molecular composition of thousands of samples arrayed on a small slide of silicon at speeds 100 times faster than conventional methods.

The JBEI GT Collection: A New Resource for Advanced Biofuels Research

The JBEI GT Collection, the first glycosyltransferase clone collection specifically targeted for the study of plant cell wall biosynthesis, features GT clones of rice (shown here) and Arabidopsis plants. (Photo by Roy Kaltschmidt)

Featured Publications